应用数学和计算致力于应用数学、数值计算和面向系统的思想在物理、生物、社会和行为科学中的应用之间的接口，并强调计算性质的论文，重点关注新的算法、它们的分析和数值结果。除了发表研究论文，应用数学和计算出版评论文章和单主题问题。
Applied Mathematics and Computation addresses work at the interface between applied mathematics, numerical computation, and applications of systems – oriented ideas to the physical, biological, social, and behavioral sciences, and emphasizes papers of a computational nature focusing on new algorithms, their analysis and numerical results.In addition to presenting research papers, Applied Mathematics and Computation publishes review articles and single–topics issues.