《生物理论学报》倡导理论生物学，涵盖数学生物学和生物学哲学，特别关注生物学理论形成的方法论。该杂志欢迎有关各种生物学理论的论文。涵盖范围包括生物学哲学、生物数学、计算生物学、遗传学、生态学和形态学。文章可以用文字或数学的形式描述理论形成的过程。该杂志有时提供纯方法论的论文，致力于生物学理论和概念背后的哲学的历史起源。Acta biotheoretical tica还出版评论性的书评、对以前论文的简短评论和对有趣的新理论观点的简短注释。
Acta Biotheoretica promotes theoretical biology, encompassing mathematical biology and the philosophy of biology, and paying special attention to the methodology of formation of biological theory.The journal welcomes papers on all kinds of biological theories. The range of coverage includes philosophy of biology, biomathematics, computational biology, genetics, ecology and morphology. Articles can present the process of theory formation in verbal or mathematical form. The journal sometimes presents purely methodological papers devoted to the historical origins of the philosophy underlying biological theories and concepts.Acta Biotheoretica also publishes critical book reviews, short commentaries on previous papers and short notes directing attention to interesting new theoretical ideas.