由自然出版集团出版。ISSN: 1359-4184。发表旨在阐明精神疾病及其治疗的生物学机制的工作。重点是临床前研究和临床研究的衔接，包括细胞、分子、整合、临床、影像学和精神药理学水平的研究。
Published by Nature Publishing Group. ISSN: 1359-4184.Publishes work aimed at elucidating biological mechanisms underlying psychiatric disorders and their treatment. The emphasis is on studies at the interface of pre-clinical and clinical research, including studies at the cellular, molecular, integrative, clinical, imaging and psychopharmacology levels.