发表关于真核细胞细胞核功能组织的研究和综述文章，特别强调染色质和染色体的结构和动力学;基因组的表达和复制;基因组组织与进化;在减数分裂和有丝分裂过程中基因组的分离;亚核室的功能和动力学;核膜和核质相互作用，等等。
Chromosoma publishes research and review articles on the functional organization of the eukaryotic cell nucleus, with a particular emphasis on the structure and dynamics of chromatin and chromosomes; the expression and replication of genomes; genome organization and evolution; the segregation of genomes during meiosis and mitosis; the function and dynamics of subnuclear compartments; the nuclear envelope and nucleocytoplasmic interactions, and more.