本杂志发表了关于抗菌、抗病毒和抗肿瘤物质的作用模式和药理特性的研究结果。虽然以实验工作为主，但也包括临床研究。为该杂志挑选的论文提供了有关新药在单独和联合应用中的有效性、毒理学和相互作用的数据。该杂志还发表了旨在确定药物动力学特性或评估类似制剂的比较疗效的研究。通过在每期杂志和定期增刊上发表大量关于抗生素和细胞抑制剂化疗的专题文章，化疗应用的增长得到了很好的服务。
This journal publishes the results of investigations into the mode of action and pharmacologic properties of antibacterial, antiviral and antitumor substances. Although experimental work predominates, clinical studies are included. Papers selected for the journal offer data concerning the efficacy, toxicology, and interaction of new drugs in single and combined applications. The journal also publishes studies designed to determine pharmacokinetic properties or evaluate the comparative efficacy of similar preparations. The growth of chemotherapeutic applications is well served through the large number of contributions published in each issue and regular supplement issues devoted to specific themes concerning antibiotic and cytostatic chemotherapy.